(-) - Riboflavin (vitamin B2) and flavin mononucleotide as visible light photo initiators in the thiol-ene polymerisation of PEG-based hydrogels

被引：55
|
作者：
Batchelor, R. R. [1 ,2 ]
Kwandou, G. [1 ]
Spicer, P. T. [1 ]
Stenzel, M. H. [2 ,3 ]
机构：
[1] Univ New South Wales, Sch Chem Engn, Sydney, NSW 2052, Australia
[2] Univ New South Wales, CAMD, Sydney, NSW 2052, Australia
[3] Univ New South Wales, Sch Chem, Sydney, NSW 2052, Australia
来源：
POLYMER CHEMISTRY | 2017年 / 8卷 / 06期
关键词：
CLICK CHEMISTRY; PHOTOPOLYMERIZATION; PHOTOINITIATOR; MONOMERS; DELIVERY; BLUE;
D O I：
10.1039/c6py02034h
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The photoinitiators used in light mediated hydrogelation have been limited due to cytotoxicity and solubility issues. Here we report the use of riboflavin and flavin mononucleotide as nontoxic, naturally occurring photoinitiators for the thiol-ene hydrogelation of functionalised poly(ethylene glycol). High Resolution Magic Angle Spinning (HRMAS) NMR spectroscopy and oscillatory rheometry were used to probe the efficiency of these initiators for this hydrogel system. The gelation and reaction progression could easily be manipulated using different initiator concentrations and light intensities.
引用
收藏
页码：980 / 984
页数：5
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