Multi-Color Single Photon Detection With Enhanced Linearity

被引:0
|
作者
Gudkov, Dmytro [1 ]
Gavrilov, Dmitri [2 ]
Kosobokova, Olga [2 ]
Gorbovitski, Boris [1 ]
Gorfinkel, Vera [2 ]
机构
[1] ABMM Inc, Setauket, NY 11733 USA
[2] SUNY Stony Brook, Stony Brook, NY 11794 USA
基金
美国国家卫生研究院;
关键词
Multi-color fluorescence; photomultipliers; photon counting; micro-beads; DYNAMIC-RANGE;
D O I
10.1109/JSEN.2015.2499279
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A new method for multi-color single photon detection with an enhanced linearity is proposed. Due to the use of the multi-channel single photon detection in conjunction with a novel approach to the post processing of the detected signal, the method provides up to an order of magnitude enhancement of the detection linearity and enables an accurate determination of color composition of fluorescence-labeled micro-objects. Application of the new method for the detection of fluorescent microbeads moving in a microfluidic channel is presented.
引用
收藏
页码:941 / 945
页数:5
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