Effects of tizanidine, a centrally acting muscle relaxant, on spinal reflex potentials in rats, with special reference to imidazoline receptors

被引：0

作者：

Sekiguchi, Y ^{[1
]}

Honda, M ^{[1
]}

Ono, H ^{[1
]}

机构：

[1] Sci Univ Tokyo, Fac Pharmaceut Sci, Dept Pharmacol, Shinjuku Ku, Tokyo 1620826, Japan

来源：

FRONTIERS OF THE MECHANISMS OF MEMORY AND DEMENTIA | 2000年 / 1200期

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D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Tizanidine decreased the mono- (MSR) and polysynaptic spinal reflexes (PSR) in rats. The inhibitory effects of tizanidine were antagonized by the alpha 2-adrenoceptor/imidazoline receptor antagonist idazoxan but not by the alpha 2-adrenoceptor antagonist yohimbine. These results suggest that the imidazoline receptors are involved in the inhibitory effects of tizanidine on spinal reflexes.

引用

页码：43 / 44

页数：2

共 38 条

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