Transgenic animals with altered high-density lipoprotein composition and functions

被引：15
|
作者：
Kalopissis, AD [1 ]
Chambaz, J [1 ]
机构：
[1] Ctr Rech Cordeliers, INSERM, U505, F-75006 Paris, France
来源：
CURRENT OPINION IN LIPIDOLOGY | 2000年 / 11卷 / 02期
关键词：
D O I：
10.1097/00041433-200004000-00007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Our understanding of HDL metabolism in vivo has greatly advanced from studies with transgenic animals, Interactions between HDL apolipoproteins, transfer proteins, lipolytic enzymes and receptors modulate HDL size, particle number and fractional catabolic rate. The protective effect of HDL on atherosclerosis depends on the combined actions of HDL proteins and the metabolism of apo B-lipoproteins. Curr Opin Lipidol 11:149-153. (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码：149 / 153
页数：5
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