Simultaneous occurrence of chronic myeloid leukemia and chronic lymphocytic leukemia: Report of an unusual case

被引:5
|
作者
Rahman, Khaliqur [1 ]
George, Seena [2 ]
Mangal, Sriyash [3 ]
Mehta, Anurag [1 ]
机构
[1] Sanjay Gandhi Postgrad Inst Med Sci, Dept Hematol, Lucknow 226014, Uttar Pradesh, India
[2] Rajiv Gandhi Canc Inst & Res Ctr, Dept Pathol, New Delhi, India
[3] Amity Univ, Dept Biotechnolocy, Noida, India
关键词
Chronic lymphocytic leukemia; chronic myeloid leukemia; immunophenotype; cytogentics; volume conductivity scatter; CHRONIC MYELOCYTIC-LEUKEMIA; CHRONIC MYELOGENOUS LEUKEMIA; CHRONIC GRANULOCYTIC-LEUKEMIA; GENOMIC EVENTS; PATIENT; EVOLUTION; CLONES; ORIGIN;
D O I
10.4103/0377-4929.125369
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The coexistence of chronic myeloid leukaemia(CML) and chronic lymphocytic leukemia(CLL) has been reported occasionally in literature, with only seven cases of simultaneous occurrence of these two diseases. We present here a case of 57 yr male patient where a complete blood count and differential done using volume conductivity scatter (VCS) technology suggested a diagnosis of CML with CLL. It was further confirmed by immunophneotyping and cytogenetic analysis. The patient was started on tyrosine kinase inhibitor, 400 mg once daily. Four months after the treatment, patient is doing fine with a count of 22 x 10(9)/L and 64% lymphocytes.
引用
收藏
页码:453 / 456
页数:4
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