A New Signal Processing Method Based on Doppler Effect for Targeted Ultrasound Contrast Agent Imaging

被引：0

作者：

Wang, Qian ^{[1
]}

Zheng, Hairong ^{[2
]}

机构：

[1] Chinese Acad Sci, Lauterbur Biomed Imaging Ctr, Shenzhen Inst Adv Technol, Inst Biomed & Hlth Engn, Beijing 100864, Peoples R China

[2] Chinese Acad Sci, CUHK Res Ctr Biosensors & Med Instruments, Inst Biomed & Hlth Engn, Shenzhen, Peoples R China

来源：

2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010) | 2010年

基金：

美国国家科学基金会;

关键词：

targeted contrast agent; ultrasound molecular imaging; Doppler frequency; wall filter; TUMOR ANGIOGENESIS; CLUTTER REJECTION; SYSTEM;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Targeted ultrasound molecular imaging technology is emerging as a novel imaging modality that shows initial successes in sensitive detecting of inflammation, heart transplant rejection, thrombus and angiogenesis. In the targeted imaging, one challenge is to detect the signal from targeted contrast microbubles. The paper presents a new targeted contrast agent imaging method which could differentiate adherent and free agents effectively by using Doppler frequency shift. The Doppler frequency shift is employed to analysis the flowing bubble signal and stationary bubble signal. The Doppler shift frequency can be calculated due to the reflecting central frequency and bandwidth in addition to the velocity of the free bubble controlled by a syringe pump in the experiment. The wall filter is applied for filtering the signal that brings up the Doppler shift frequency. By using the method, experimental study shows compressed the free contrast agent and tissue signals while leaving the targeted bubble signal unaffected.

引用

页数：4

共 50 条

[1] SIGNAL-PROCESSING IN ULTRASOUND IMAGING, DOPPLER AND DOPPLER IMAGING
BURCKHARDT, CB
[J]. ULTRASCHALL IN DER MEDIZIN, 1993, 14 (05): : 220 - 224
[2] SURF Imaging - A new method for ultrasound contrast agent Imaging
Angelsen, Bjorn A. J.
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[3] Ultrasound contrast agent harmonic imaging method based on frequency-modulated signal excitation
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[4] Modification of surfactant contrast agent for targeted ultrasound imaging
Oeffinger, BE
Lathia, JD
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Barbee, KA
Wheatley, MA
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[5] Harmonic chirp imaging method for ultrasound contrast agent
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Versluis, M
de Jong, N
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Hall, CS
Abendschein, DR
Scherrer, DE
Scott, MJ
Fuhrhop, RJ
Gaffney, PJ
Wickline, SA
Lanza, GM
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Forghani, F.
Mahl, A.
Shakya, G.
Borden, M.
Patton, T.
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Jones, B.
Miften, M.
Thomas, D.
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[10] Doppler photoacoustic and Doppler ultrasound in blood with optical contrast agent
Sheinfeld, Adi
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[J]. PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2013, 2013, 8581

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