Sonication-Assisted Nanoprecipitation in Drug Delivery

被引：6

作者：

Anh Thi Ngoc Vo ^{[1
]}

Thinh Duc Luu ^{[1
]}

Minh Ngoc Uyen Nguyen ^{[1
]}

Toi Van Vo ^{[1
]}

Duan, Wei ^{[2
]}

Phuong Ha-Lien Tran ^{[2
]}

Thao Truong-Dinh Tran ^{[1
]}

机构：

[1] Vietnam Natl Univ, Int Univ, Dept Biomed Engn, Pharmaceut Engn Lab, Ho Chi Minh City, Vietnam

[2] Deakin Univ, Sch Med, Waurn Ponds, Vic, Australia

来源：

CURRENT DRUG METABOLISM | 2017年 / 18卷 / 02期

关键词：

Nanoprecipitation; sonication; ultrasonication; drug delivery; WATER-SOLUBLE DRUGS; CEFUROXIME AXETIL NANOPARTICLES; INLET VORTEX MIXER; ANTISOLVENT PRECIPITATION; EVAPORATIVE PRECIPITATION; PARTICLE-SIZE; DISSOLUTION RATE; SOLID DISPERSIONS; SAMPLE TREATMENT; SOLUBILITY;

D O I：

10.2174/1389200218666170116103555

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sonication-assisted nanoprecipitation provides an effective tool for nanomedicine engineering in therapeutic improvement. In the scope of this review, original works in interdisciplinary areas of using sonication with precipitation method for nanoparticulate drug delivery systems and its applications in management of different diseases are discussed. The use of sonication-assisted nanoprecipitation has been proved to improve drug bioavailability, which attracts tremendous interests as an effective strategy for drug delivery. However, many challenges still remain. To overcome these barriers, different approaches such as precipitation method, rational design, optimization and modification have been investigated. Accordingly, current knowledge of sonication-assisted nanoprecipitation proposes a broad perspective and optimization for the applications of nanotechnology in drug delivery.

引用

页码：145 / 156

页数：12

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