Moringa oleifera Lam and its Therapeutic Effects in Immune Disorders

被引:30
|
作者
Xiao, Xiao [1 ,2 ,3 ,4 ]
Wang, Jue [5 ]
Meng, Chen [4 ]
Liang, Weibo [4 ]
Wang, Tao [3 ]
Zhou, Bin [3 ]
Wang, Yanyun [3 ]
Luo, Xiaolei [3 ]
Gao, Linbo [3 ]
Zhang, Lin [3 ,4 ]
机构
[1] Sichuan Univ, West China Univ Hosp 2, Dept Obstet & Gynecol, Chengdu, Peoples R China
[2] Sichuan Univ, Key Lab Birth Defects & Related Dis Women & Child, Minist Educ, Chengdu, Peoples R China
[3] Sichuan Univ, Lab Mol Translat Med, Ctr Translat Med,Minist Educ,West China Univ Hosp, Key Lab Birth Defects & Related Dis Women & Child, Chengdu, Peoples R China
[4] Sichuan Univ, West China Sch Basic Med Sci & Forens Med, Dept Forens Genet, Chengdu, Peoples R China
[5] Chengdu Second Peoples Hosp, Dept Geriatr, Chengdu, Peoples R China
来源
FRONTIERS IN PHARMACOLOGY | 2020年 / 11卷
基金
中国国家自然科学基金;
关键词
Moringa oleifera; infection; chronic inflammation; physicochemical irritation; autoimmune disorders; GUINEA-PIG MODEL; LEAF EXTRACT; ANTIOXIDANT ACTIVITY; AIRWAY INFLAMMATION; HEAVY-METALS; SEEDS; FRACTION; BIOSORPTION; TOXICITY; REMOVAL;
D O I
10.3389/fphar.2020.566783
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Moringa oleifera Lam., a plant native to tropical forests of India, is characterized by its versatile application as a food additive and supplement therapy. Accumulating evidence shows that Moringa plays a critical role in immune-related diseases. In this review, we cover the history, constituents, edibility, and general medicinal value of Moringa. The effects of Moringa in treating immune disorders are discussed in detail. Moringa can not only eliminate pathogens, including bacteria, fungi, viruses, and parasites, but also inhibit chronic inflammation, such as asthma, ulcerative colitis, and metabolic diseases. Additionally, Moringa can attenuate physical and chemical irritation-induced immune disorders, such as metal intoxication, drug side effects, or even the adverse effect of food additives. Autoimmune diseases, like rheumatoid arthritis, atopic dermatitis, and multiple sclerosis, can also be inhibited by Moringa. Collectively, Moringa, with its multiple immune regulatory bioactivities and few side effects, has a marked potential to treat immune disorders.
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页数:9
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