INTRADISCAL DELIVERY OF CELECOXIB-LOADED MICROSPHERES RESTORES DISC HOMEOSTASIS IN A PRECLINICAL CANINE MODEL OF INTERVERTEBRAL DISC DEGENERATION

被引:0
|
作者
Tellegen, A. R. [1 ]
Jansen, I. [2 ]
Beukers, M. [1 ]
Miranda-Bedate, A. [1 ]
De Jong, W. [1 ]
Woike, N. [3 ]
Thies, J. C. [3 ]
Mihov, G. [3 ]
Meij, B. P. [1 ]
Creemers, L. B. [2 ]
Tryfonidou, M. A. [1 ]
机构
[1] Univ Utrecht, Utrecht, Netherlands
[2] Univ Med Hosp, Utrecht, Netherlands
[3] DSM Res & Patents, Geleen, Netherlands
关键词
D O I
10.1016/j.joca.2018.02.808
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
768
引用
收藏
页码:S418 / S419
页数:2
相关论文
共 37 条
  • [1] Intradiscal delivery of celecoxib-loaded microspheres restores intervertebral disc integrity in a preclinical canine model
    Tellegen, A. R.
    Rudnik-Jansen, I.
    Beukers, M.
    Miranda-Bedate, A.
    Bach, F. C.
    de Jong, W.
    Woike, N.
    Mihov, G.
    Thies, J. C.
    Meij, B. P.
    Creemers, L. B.
    Tryfonidou, M. A.
    [J]. JOURNAL OF CONTROLLED RELEASE, 2018, 286 : 439 - 450
  • [2] Safety of intradiscal injection and biocompatibility of polyester amide microspheres in a canine model predisposed to intervertebral disc degeneration
    Willems, Nicole
    Mihov, George
    Grinwis, Guy C. M.
    van Dijk, Maarten
    Schumann, Detlef
    Bos, Clemens
    Strijkers, Gustav J.
    Dhert, Wouter J. A.
    Meij, Bjorn P.
    Creemers, Laura B.
    Tryfonidou, Marianna A.
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2017, 105 (04) : 707 - 714
  • [3] Local Delivery of Senolytic Drug Inhibits Intervertebral Disc Degeneration and Restores Intervertebral Disc Structure
    Lim, Songhyun
    An, Seong Bae
    Jung, Mungyo
    Joshi, Hari Prasad
    Kumar, Hemant
    Kim, Cheesue
    Song, Seuk Young
    Lee, Ju-Ro
    Kang, Mikyung
    Han, Inbo
    Kim, Byung-Soo
    [J]. ADVANCED HEALTHCARE MATERIALS, 2022, 11 (02)
  • [4] The Thermosensitive Injectable Celecoxib-Loaded Chitosan Hydrogel for Repairing Postoperative Intervertebral Disc Defect
    Du, Yukun
    Li, Jianyi
    Tang, Xiaojie
    Liu, Yingying
    Bian, Guoshuai
    Shi, Jianzhuang
    Zhang, Yixin
    Zhao, Baomeng
    Zhao, Hongri
    Sui, Kunyan
    Xi, Yongming
    [J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 10
  • [5] Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
    Nicole Willems
    Frances C Bach
    Saskia G M Plomp
    Mattie HP van Rijen
    Jeannette Wolfswinkel
    Guy CM Grinwis
    Clemens Bos
    Gustav J Strijkers
    Wouter JA Dhert
    Björn P Meij
    Laura B Creemers
    Marianna A Tryfonidou
    [J]. Arthritis Research & Therapy, 17
  • [6] Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
    Willems, Nicole
    Bach, Frances C.
    Plomp, Saskia G. M.
    van Rijen, Mattie H. P.
    Wolfswinkel, Jeannette
    Grinwis, Guy C. M.
    Bos, Clemens
    Strijkers, Gustav J.
    Dhert, Wouter J. A.
    Meij, Bjorn P.
    Creemers, Laura B.
    Tryfonidou, Marianna A.
    [J]. ARTHRITIS RESEARCH & THERAPY, 2015, 17
  • [7] Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression
    Wang, Yunhao
    Zheng, Genjiang
    Xie, Xiaoxing
    Yu, Wei
    Wang, Jianxi
    Zang, Fazhi
    Yang, Chen
    Xiao, Qiangqiang
    Zhang, Rongcheng
    Wei, Leixin
    Wu, Xiaodong
    Liang, Lei
    Cao, Peng
    Xu, Chen
    Li, Jing
    Hu, Bo
    Zhang, Tao
    Wu, Jinglei
    Chen, Huajiang
    [J]. JOURNAL OF NANOBIOTECHNOLOGY, 2023, 21 (01)
  • [8] Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression
    Yunhao Wang
    Genjiang Zheng
    Xiaoxing Xie
    Wei Yu
    Jianxi Wang
    Fazhi Zang
    Chen Yang
    Qiangqiang Xiao
    Rongcheng Zhang
    Leixin Wei
    Xiaodong Wu
    Lei Liang
    Peng Cao
    Chen Xu
    Jing Li
    Bo Hu
    Tao Zhang
    Jinglei Wu
    Huajiang Chen
    [J]. Journal of Nanobiotechnology, 21
  • [9] Intradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model
    Takao Sudo
    Koji Akeda
    Koki Kawaguchi
    Takahiro Hasegawa
    Junichi Yamada
    Nozomu Inoue
    Koichi Masuda
    Akihiro Sudo
    [J]. Arthritis Research & Therapy, 23
  • [10] Evaluation of Percutaneous Intradiscal Amniotic Suspension Allograft in a Rabbit Model of Intervertebral Disc Degeneration
    Luo, Tianyi David
    Vines, Jeremy B.
    Zabarsky, Zachary K.
    Mowry, Katie C.
    Marquez-Lara, Alejandro
    Jinnah, Alexander H.
    Ma, Xue
    Berwick, Benjamin W.
    Willey, Jeffrey S.
    Smith, Thomas L.
    Li, Zhongyu
    O'Gara, Tadhg J.
    [J]. SPINE, 2019, 44 (06) : E329 - E337