Primary breast angiosarcoma: Two cases report

Primary angiosarcoma is a rare type of breastcancer, the diagnosis is difficult to establish and it has the worst prognostic of all breast malignancies. Two cases of primary breast angiosarcoma have been observed at the centre Henry Kaplan of Tours and at the hospital La Source of Orleans since 2001. Based on a literature review, we analyse the epidemiological, pathological, clinical, diagnostic and treatment aspect of this type of cancer. Mastectomy is the reference treatment and the benefit of radiotherapy and chemotherapy remains to be demonstrated. (C) 2009 Published by Elsevier Masson SAS on behalf of the Societe francaise de radiotherapie oncologique (SFRO).