Chemical composition and antimicrobial activity of Satureja hortensis L. essential oil

被引:56
|
作者
Mihajilov-Krstev, Tatjana [1 ]
Radnovic, Dragan [2 ]
Kitic, Dusanka [3 ]
Zlatkovic, Bojan [1 ]
Ristic, Mihailo [4 ]
Brankovic, Suzana [3 ]
机构
[1] Univ Nis, Dept Biol & Ecol, Nish 18000, Serbia
[2] Univ Novi Sad, Dept Biol & Ecol, Novi Sad 21000, Serbia
[3] Univ Nis, Fac Med, Nish 18000, Serbia
[4] Inst Med Plant Res Dr Josif Pancic, Belgrade 11000, Serbia
来源
CENTRAL EUROPEAN JOURNAL OF BIOLOGY | 2009年 / 4卷 / 03期
关键词
Satureja L; S; hortensis; Essential oil; Antimicrobial activity; Wound infection; OREGANO ESSENTIAL OIL; ASPERGILLUS-FLAVUS; METHANOL EXTRACT; SUMMER SAVORY; ANTIBACTERIAL; ANTIFUNGAL; CARVACROL; ANTIOXIDANT; INHIBITION; THYMOL;
D O I
10.2478/s11535-009-0027-z
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Essential oil of Satureja hortensis L. was analyzed by GC and GC/MS and tested by a broth micro-well dilution method for activity against multiresistant clinical isolates of pathogenic bacteria from 10 different genera: Klebsiella, Escherichia, Proteus, Staphylococcus, Streptococcus, Pseudomonas, Enterococcus, Enterobacter, Citrobacter and Acinetobacter. The main compounds in the oil were carvacrol (67%), gamma-terpinene (15.3%) and p-cymene (6.73%). The oil showed activity against all tested strains. MIC/MBC values were in the range of 0.78-25 mu l/ml, with the exception of the strain P. aeruginosa. Microbicidal concentration for this particular strain (50 mu l/ml) was the highest tested concentration. The oil showed inhibitory and bactericidal effect at the same concentration (MIC=MBC) for all but three strains.
引用
收藏
页码:411 / 416
页数:6
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