Helminths and our immune system: Friend or foe?

被引:24
|
作者
Helmby, Helena [1 ]
机构
[1] London Sch Hyg & Trop Med, Immunol Unit, Dept Infect & Trop Med, London WC1E 7HT, England
基金
英国惠康基金;
关键词
Helminth; Nematode; Trematode; Plasmodium; Immunity; Autoimmunity; Allergy; Vaccination; Co-infection; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; SCHISTOSOMA-MANSONI INFECTION; PLASMODIUM-FALCIPARUM MALARIA; ALLERGIC AIRWAY INFLAMMATION; ASCARIS-LUMBRICOIDES INFECTION; CONCURRENT NEMATODE INFECTION; TRICHURIS-SUIS THERAPY; VACCINE CVD 103-HGR; BLOOD-STAGE MALARIA; REGULATORY T-CELLS;
D O I
10.1016/j.parint.2009.02.001
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Helminths are able to modulate and Suppress the hosts' immune response in order to promote their own Survival. This ability to alter immune responses Could be of potential detriment to the host if it interferes with the development of protective immune responses against other infections. However, helminth infections have also been Suggested to be beneficial in the control of excessive inflammatory, reactions. In this review I will highlight some of the data Suggesting both positive and negative effects of helminth infections in humans and in experimental models. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:121 / 127
页数:7
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