Synthesis of β-Allylbutenolides via One-Pot Copper-Catalyzed Hydroallylation/Cyclization of γ-Hydroxybutynoate Derivatives

被引：16

作者：

Yamamoto, Yoshihiko ^{[1
]}

Shibano, Shinya ^{[1
]}

Kurohara, Takashi ^{[1
]}

Shibuya, Masatoshi ^{[1
]}

机构：

[1] Nagoya Univ, Dept Basic Med Sci, Grad Sch Pharmaceut Sci, Chikusa Ku, Nagoya, Aichi 4648601, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 79卷 / 10期

关键词：

RING-CLOSING METATHESIS; EFFICIENT SYNTHESIS; CYCLIZATION; FLUORINE; HYDROARYLATION; CHEMISTRY; BUTENOLIDES; PHARMACEUTICALS; PENTENOLIDES; ALKYNES;

D O I：

10.1021/jo500536b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One-pot copper-catalyzed hydroallylation/lactone cyclization of gamma-hydroxybutynoate derivatives was developed to afford beta-allylbutenolides.

引用

下载

页码：4503 / 4511

页数：9

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