Coxsackievirus A6 and enterovirus 71 causing hand, foot and mouth disease in Cuba, 2011-2013

被引：36
|
作者：
Fonseca, Magile C. [1 ]
Sarmiento, Luis [1 ]
Resik, Sonia [1 ]
Martinez, Yenisleidys [1 ]
Heng Hung, Lai [1 ]
Morier, Luis [1 ]
Pinon, Alexander [1 ]
Valdez, Odalys [1 ]
Kouri, Vivian [1 ]
Gonzalez, Guelsys [1 ]
机构：
[1] Pedro Kouri Trop Med Inst, Havana 11400, Cuba
来源：
ARCHIVES OF VIROLOGY | 2014年 / 159卷 / 09期
关键词：
OUTBREAK; PCR; IDENTIFICATION; AMPLIFICATION; SEQUENCES; STRAINS; VP1; A10;
D O I：
10.1007/s00705-014-2071-x
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Hand, foot and mouth disease (HFMD) is usually caused by coxsackievirus A16 or enterovirus 71 (EV71). Between 2011 and 2013, HFMD cases were reported from different Cuban provinces. A total of 42 clinical specimens were obtained from 23 patients. Detection, identification and phylogenetic analysis of enterovirus-associated HFMD were carried out by virus isolation, specific enterovirus PCR and partial VP1 sequences. HEV was detected in 11 HFMD cases. Emerging genetic variants of coxsackievirus A6 and EV71 were identified as the causative agents of the Cuban HFMD cases.
引用
收藏
页码：2451 / 2455
页数：5
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