Cross-over trials in Statistics in Medicine:: The first '25' years

被引：66
|
作者：
Senn, Stephen [1 ]
机构：
[1] Univ Glasgow, Dept Stat, Glasgow G12 8QQ, Lanark, Scotland
来源：
STATISTICS IN MEDICINE | 2006年 / 25卷 / 20期
关键词：
baselines; bioequivalence; binary data; carry-over; survival analysis;
D O I：
10.1002/sim.2706
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Papers on cross-over trials that have appeared in the first 25 years of Statistics in Medicine are reviewed. Papers on bioequivalence are also considered. After a brief statistical summary, individual papers are discussed under seven headings: 1. The two-stage analysis of AB/BA trials, 2. Baselines, 3. Binary and categorical data, 4. Survival data, 5. Modelling carry-over, 6. Bioequivalence and 7. Components of variation. Finally, a brief assessment of the importance in this field of Statistics in Medicine is given. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码：3430 / 3442
页数：13
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