Silent cerebral infarction: Not so silent after all

被引：3
|
作者：
Pavlakis, Steven G. [1 ]
Roach, E. Steve [2 ]
机构：
[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[2] Ohio State Univ, Columbus, OH 43210 USA
来源：
NEUROLOGY | 2018年 / 90卷 / 03期
关键词：
SICKLE-CELL-ANEMIA; CHILDREN; DISEASE;
D O I：
10.1212/WNL.0000000000004839
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The occurrence of large cerebral infarctions due to sickle cell disease (SCD) has been known for many years, but it was not until 1988 that brain MRI documented 7 lesions consistent with subclinical infarction in 6 children with SCD who had experienced no prior signs or symptoms of stroke.(1) Five of these 6 children had T2 hyperintensity abnormalities located in border zone regions. Such lesions were eventually characterized as a silent cerebral infarction (SCI). The presence of SCIs predicts both future SCIs and overt stroke.(2</SUP)
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页码：105 / 106
页数：2
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