A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

被引:32
|
作者
Ye, Sujuan [1 ,2 ]
Wu, Yanying [2 ]
Zhang, Wen [1 ]
Li, Na [1 ]
Tang, Bo [1 ]
机构
[1] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes,Minist Educ, Jinan 250014, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
基金
中国国家自然科学基金;
关键词
ENHANCED RAMAN-SCATTERING; AMPLIFIED DETECTION; DNA; PLATFORM; BEACONS;
D O I
10.1039/c4cc03988b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.
引用
收藏
页码:9409 / 9412
页数:4
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