Alveolar Reconstruction Using Stem Cells in Patients with Cleft Lip and Palate: A Systematic Review

被引：2
|
作者：
Almotawah, Fatmah Nasser [1 ]
AlNamasy, Reyam [2 ]
Alhamazani, Bandar [3 ]
Almohsen, Sokina [4 ]
AlNamasy, Razan Emad [5 ]
机构：
[1] Riyadh Elm Univ, Dept Prevent Dent, Riyadh, Saudi Arabia
[2] Imam Abdulrahman bin Faisal Univ, Dept Dent, Riyadh, Saudi Arabia
[3] Univ Hail, Dept Dent, Al Safa Med Complex, Hail, Saudi Arabia
[4] Dept Dent, Gainesville, FL USA
[5] Private Clin, Dept Dent, Dammam, Saudi Arabia
来源：
ARCHIVES OF PHARMACY PRACTICE | 2022年 / 13卷 / 04期
关键词：
Cleft lip; Cleft palate; Stem cells; Alveolar reconstruction; EXFOLIATED DECIDUOUS TEETH; ADIPOSE-TISSUE; BONE; DIFFERENTIATION; REPAIR;
D O I：
10.51847/IoBhDeHRqO
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Mesenchymal stem cells (MSCs) isolated from dental tissues have also been studied extensively recently due to their relatively easy availability. The researchers have been working on improving a method for regenerating alveolar bone in patients with cleft lip and palate utilizing mesenchymal stem cells isolated from human bone marrow (hBMSCs). A systematic literature review from 2010 to 2022 was performed using PubMed, Medline, and ScienceDirect databases. The keywords used were "cleft lip," "cleft palate," "and stem cells," and "alveolar reconstruction." In addition, the PRISMA flowchart was used to describe the selection process of searched articles. A total of 9 studies were included in this systematic review, out of which the majority revealed successful treatment of cleft lip and palate using various kinds of stem cells. Although various types of stem cells have shown encouraging outcomes regarding bone regeneration and the treatment of cleft lip and palate, the most effective was mesenchymal stem cells, followed by adipose stem cells.
引用
收藏
页码：57 / 62
页数：6
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