PtxNi/C nanostructured composites fabricated by chemical reduction and their application in non-enzymatic glucose sensors

Platinum-cobalt PtxNi alloy nanoparticles have been successfully fabricated by the chemical reduction method, using carbon (Vulcan XC-72) as support. The resulting modified glassy carbon electrode shows excellent catalytic activity for the oxidation of glucose. Under physiological conditions, the oxidation current of glucose has two specific linear ranges of 2.0-420 mu M and 0.5-8.5 mM, with high sensitivities of 1795.1 mu A mM(-1) cm(-2) and 707.72 mu A mM(-1) cm(-2), respectively. In addition, interference from the oxidation of ascorbic acid, uric acid, or acetamidophenol could be effectively avoided. The non-enzymatic glucose sensors based on this electrode exhibited excellent selectivity, stability, and repeatability. Thus, this novel non-enzyme sensor has potential application in glucose detection. (C) 2014 Elsevier B.V. All rights reserved.