Monoamine oxidase inhibitory activity of the total alkaloid and organic acid from Chinese herbal medicines

被引：4
|
作者：
Yang, Zhongduo [1 ]
Ren, Jin [1 ]
Shu, Zongmei [1 ]
机构：
[1] Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China
来源：
ADVANCES IN CHEMICAL ENGINEERING III, PTS 1-4 | 2013年 / 781-784卷
关键词：
Chinese herbal medicine; MAO inhibitors; organic acid; alkaloid;
D O I：
10.4028/www.scientific.net/AMR.781-784.899
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
The aim of this study was to search for potential monoamine oxidase (MAO) inhibitors from Chinese herbal medicine. The organic acid extracts of 34 and the total alkaloidal extracts of 30 traditional Chinese medicines were tested for their MAO inhibitory activities. The results showed that the organic acid extracts of Liquidambar formosana, Pharbitis nil, Punica granatum and alkaloid extracts of Coptis chinensis exhibited the most potent inhibition on MAO and their concentration that inhibited 50% of MAO activity (IC50) values less than 10 mu g/mL.
引用
收藏
页码：899 / 902
页数：4
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