Insulin-like growth factor 1 and muscle growth: implication for satellite cell proliferation

被引:92
|
作者
Machida, S
Booth, FW
机构
[1] Univ Missouri, Dept Biomed Sci, Columbia, MO 65211 USA
[2] Univ Missouri, Dept Med Pharmacol & Physiol, Columbia, MO 65211 USA
[3] Univ Missouri, Dalton Cardiovasc Ctr, Columbia, MO 65211 USA
关键词
insulin-like growth factor 1; satellite cells;
D O I
10.1079/PNS2004354
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Insulin-like growth factor 1 (IGF-1) has been shown to rescue the aging-related or inactivity-induced loss of muscle mass through the activation of satellite cells. However, the signalling pathways and the mechanism by which IGF-1 affects satellite cells have not been not completely identified. The purpose of the present review is to provide current understanding of the cellular and molecular events underlying IGF-1 induced proliferation of satellite cells.
引用
收藏
页码:337 / 340
页数:4
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