Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia - accelerated phase: A rare case with review of the literature

被引：4

作者：

Kumar, Narender ^{[1
]}

Ahluwalia, Jasmina ^{[1
]}

Malhotra, Pankaj ^{[2
]}

Sachdeva, Man Updesh Singh ^{[1
]}

机构：

[1] Postgrad Inst Med Educ & Res, Dept Hematol, Chandigarh 160012, India

[2] Postgrad Inst Med Educ & Res, Dept Internal Med, Chandigarh 160012, India

来源：

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY | 2013年 / 56卷 / 03期

关键词：

Bone marrow; chronic lymphocytic leukemia; chronic myelogenous leukemia; flow cytometry; imatinib; CHRONIC MYELOID-LEUKEMIA; GENOMIC EVENTS; PATIENT; THERAPY;

D O I：

10.4103/0377-4929.120406

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL) are two different and common hematological neoplasms. Their coexistence is rare, especially CLL developing in a patient of CML. Till date, only a few cases are reported and all had chronic myeloid leukemia - chronic phase earlier. We report the first case of CLL developing in a patient initially diagnosed in an accelerated phase of chronic myeloid leukemia. The clonality of both CML and CLL was proven by cytogenetic, molecular and flow cytometric studies.

引用

页码：303 / 305

页数：3

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