Thyroid Stimulating Hormone Suppression in the Long-term Follow-up of Differentiated Thyroid Cancer

被引：20
|
作者：
Freudenthal, B. [1 ]
Williams, G. R. [1 ]
机构：
[1] Imperial Coll London, Mol Endocrinol Lab, Hammersmith Campus,10N5 Commonwealth Bldg, London W12 0NN, England
来源：
CLINICAL ONCOLOGY | 2017年 / 29卷 / 05期
关键词：
Differentiated thyroid cancer; subclinical thyrotoxicosis; TSH suppression; SERUM THYROTROPIN CONCENTRATIONS; ATRIAL-FIBRILLATION; TSH SUPPRESSION; SUBCLINICAL HYPERTHYROIDISM; CARDIOVASCULAR MORTALITY; THERAPY; CARCINOMA; RISK; LEVOTHYROXINE; MANAGEMENT;
D O I：
10.1016/j.clon.2016.12.011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Differentiated thyroid cancer is the most common form of thyroid cancer and its prognosis is favourable in most cases. Suppression of thyroid stimulating hormone (TSH) by supra-physiological thyroid hormone replacement has been the mainstay of long-term management for over 60 years. However, evidence for a beneficial outcome of TSH suppression is conflicting and intervention must be balanced against adverse effects, particularly affecting the cardiovascular system and skeleton. Here we discuss the role of TSH suppression in the long-term management of differentiated thyroid cancer in the context of risk stratification for disease recurrence and the latest clinical guidelines. (C) 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：325 / 328
页数：4
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