Transcriptional pausing caught in the act

被引:3
|
作者
von Hippel, Peter H. [1 ]
机构
[1] Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA
[2] Univ Oregon, Dept Chem, Eugene, OR 97403 USA
关键词
D O I
10.1016/j.cell.2006.06.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Single-molecule techniques now permit the tracking of a transcription complex along a DNA template in real time and to 1 bp resolution. As reported in this issue of Cell, Herbert et al. (2006) exploit this approach to study a central component of transcription regulation, the sequence-dependent pausing of RNA polymerase during transcript elongation.
引用
收藏
页码:1027 / 1029
页数:3
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