Very Small Embryonic-Like Stem Cells (VSELs) An Update and Future Directions

被引：103
|
作者：
Ratajczak, Mariusz Z. [1 ,2 ,3 ]
Ratajczak, Janina [1 ]
Kucia, Magda [1 ,2 ,3 ]
机构：
[1] Univ Louisville, Stem Cell Inst, James Graham Brown Canc Ctr, 500 S Floyd St,Room 107, Louisville, KY 40202 USA
[2] Warsaw Med Univ, Dept Regenerat Med, Warsaw, Poland
[3] Warsaw Med Univ, Ctr Preclin Res & Technol, Warsaw, Poland
来源：
CIRCULATION RESEARCH | 2019年 / 124卷 / 02期
基金：
美国国家卫生研究院;
关键词：
adult; embryonic stem cells; germ layers; pluripotent stem cells; teratoma;
D O I：
10.1161/CIRCRESAHA.118.314287
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Results from at least 20 independent laboratories indicate that adult tissues contain rare, early-development stem cells known as very small embryonic-like stem cells (VSELs), which can differentiate into cells from >1 germ layer. Further research on these cells may provide a path forward to application of these cells in regenerative medicine that perhaps may solve several problems inherent in the use of controversial embryonic stem cells (ESCs) and somehow problematic induced pluripotent stem cells (iPSCs).
引用
收藏
页码：208 / 210
页数：3
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