S1P1 signaling just keeps going and going and going ...

被引：2

作者：

Cahalan, Stuart ^{[1
]}

Rosen, Hugh

机构：

[1] Scripps Res Inst, Dept Physiol Chem, La Jolla, CA 92037 USA

来源：

NATURE CHEMICAL BIOLOGY | 2009年 / 5卷 / 06期

关键词：

RECEPTOR AGONISTS; LYMPHOCYTE EGRESS; 1-PHOSPHATE; S1P(1); VIVO;

D O I：

10.1038/nchembio0609-377

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthetic agonists of sphingosine-1-phosphate receptor subtype 1 are able to generate long-term signaling that persists for hours after ligand-induced receptor internalization. These signals are independent of agonist potency, can be reversed after receptor internalization by specific antagonists, and show a distinct acyl-chain-length structure-activity relationship.

引用

页码：377 / 378

页数：3

共 50 条

[1] S1P1 signaling just keeps going and going and going...
Stuart Cahalan
Hugh Rosen
[J]. Nature Chemical Biology, 2009, 5 : 377 - 378
[2] Erratum: S1P1 signaling just keeps going and going and going...
Stuart Cahalan
Hugh Rosen
[J]. Nature Chemical Biology, 2009, 5 : 954 - 954
[3] S1P1 signaling just keeps going and going and going ... (vol 5, pg 377, 2009)
Cahalan, Stuart
Rosen, Hugh
[J]. NATURE CHEMICAL BIOLOGY, 2009, 5 (12) : 954 - 954
[4] Rental equipment industry growth: It just keeps going and going and going
Yengst, CR
[J]. DIESEL PROGRESS NORTH AMERICAN EDITION, 1999, 65 (10): : 4 - 4
[5] It keeps going and going
Smith, BM
[J]. PHI DELTA KAPPAN, 1996, 77 (06) : 394 - 394
[6] The crisis that keeps going ... and going ... and going
Kesner, Idalene F.
[J]. BUSINESS HORIZONS, 2012, 55 (02) : 119 - 121
[7] A rabbit model of the brain and cardiopulmonary bypass - The bunny that just keeps going and going and going ...
Rogers, AT
[J]. ANESTHESIOLOGY, 1998, 88 (03) : 565 - 566
[8] Mutation keeps going and going
Minkel, JR
[J]. SCIENTIFIC AMERICAN, 2002, 287 (01) : 32 - 32
[9] SuperH keeps going and going
不详
[J]. COMPUTER DESIGN, 1998, 37 (02): : 86 - 86
[10] Raid keeps going and going and ...
Friedman, MB
[J]. IEEE SPECTRUM, 1996, 33 (04) : 73 - 79

← 1 2 3 4 5 →