Intraosseous Administration of Tissue Plasminogen Activator on a Mobile Stroke Unit

被引：3
|
作者：
Bowry, Ritvij [1 ]
Nour, May [2 ,3 ]
Kus, Teresa [1 ]
Parker, Stephanie [1 ]
Stephenson, Jonathan
Saver, Jeffrey
Grotta, James C. [4 ]
Ostermayer, Daniel [5 ]
机构：
[1] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Neurol, Houston, TX 77030 USA
[2] Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA
[3] Univ Calif Los Angeles, Comprehens Stroke Ctr, Los Angeles, CA USA
[4] Mem Hermann Hosp, Clin Innovat & Res Inst, Houston, TX USA
[5] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Emergency Med, Houston, TX 77030 USA
来源：
PREHOSPITAL EMERGENCY CARE | 2019年 / 23卷 / 04期
关键词：
stroke tissue plasminogen activator; mobile stroke unit; prehospital; tPA; INTRAVENOUS LINE PLACEMENT; ACUTE ISCHEMIC-STROKE; SYSTEMIC FIBRINOLYSIS; TRANEXAMIC ACID; VASCULAR ACCESS; THROMBOLYSIS; CARE; COMPLICATION; BIOAVAILABILITY; ANGIOGRAPHY;
D O I：
10.1080/10903127.2018.1526355
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Objective: Mobile stroke units offer improved time to administration of thrombolytics for ischemic stroke patients. Acquisition of intravenous (IV) access, however, can be challenging in the prehospital environment leading to treatment delays. Intraosseous (IO) access is commonly used in the prehospital setting for a variety of conditions and may serve as a viable means for tPA (tissue plasminogen activator) administration. Methods/Results: We describe 3 cases in which tPA was administered via IO access on a mobile stroke unit as part of the Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services (BEST-MSU) trial. Conclusion: No adverse events were observed in the process of obtaining IO access or administering tPA.
引用
收藏
页码：447 / 452
页数：6
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