Prevalence and Outcomes of Frailty in Korean Elderly Population: Comparisons of a Multidimensional Frailty Index with Two Phenotype Models

被引:98
|
作者
Jung, Hee-Won [1 ,5 ]
Kim, Sun-Wook [1 ,5 ]
Ahn, Soyeon [2 ]
Lim, Jae-Young [3 ,5 ]
Han, Ji-Won [4 ,5 ]
Kim, Tae-Hui [4 ,5 ]
Kim, Ki-Woong [4 ,5 ,6 ]
Kim, Kwang-il [1 ,5 ]
Kim, Cheol-Ho [1 ,5 ]
机构
[1] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea
[2] Seoul Natl Univ, Bundang Hosp, Med Res Collaborating Ctr, Songnam, South Korea
[3] Seoul Natl Univ, Bundang Hosp, Dept Rehabil, Songnam, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Dept Neuropsychiat, Songnam, South Korea
[5] Seoul Natl Univ, Coll Med, Seoul, South Korea
[6] Seoul Natl Univ, Coll Nat Sci, Dept Brain & Cognit Sci, Seoul 151742, South Korea
来源
PLOS ONE | 2014年 / 9卷 / 02期
关键词
OLDER-ADULTS; HEALTH; PREDICTION; DISABILITY; MORTALITY; DEATH;
D O I
10.1371/journal.pone.0087958
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background: Frailty is related to adverse outcomes in the elderly. However, current status and clinical significance of frailty have not been evaluated for the Korean elderly population. We aimed to investigate the usefulness of established frailty criteria for community-dwelling Korean elderly. We also tried to develop and validate a new frailty index based on a multidimensional model. Methods: We studied 693 participants of the Korean Longitudinal Study on Health and Aging (KLoSHA). We developed a new frailty index (KLoSHA Frailty Index, KFI) and compared predictability of it with the established frailty indexes from the Cardiovascular Health Study (CHS) and Study of Osteoporotic Fracture (SOF). Mortality, hospitalization, and functional decline were evaluated. Results: The prevalence of frailty was 9.2% (SOF index), 13.2% (CHS index), and 15.6% (KFI). The criteria from CHS and KFI correlated with each other, but SOF did not correlate with KFI. During the follow-up period (5.6 +/- 0.9 years), 97 participants (14.0%) died. Frailty defined by KFI predicted mortality better than CHS index (c-index: 0.713 and 0.596, respectively; p<0.001, better for KFI). In contrast, frailty by SOF index was not related to mortality. The KFI showed better predictability for following functional decline than CHS index (area under the receiver-operating characteristic curve was 0.937 for KFI and 0.704 for CHS index, p = 0.001). However, the SOF index could not predict subsequent functional decline. Frailty by the KFI (OR = 2.13, 95% CI 1.04-4.35) and CHS index (OR = 2.24, 95% CI 1.05-4.76) were associated with hospitalization. In contrast, frailty by the SOF index was not correlated with hospitalization (OR = 1.43, 95% CI 0.68-3.01). Conclusion: Prevalence of frailty was higher in Korea compared to previous studies in other countries. A novel frailty index (KFI), which includes domains of comprehensive geriatric assessment, is a valid criterion for the evaluation and prediction of frailty in the Korean elderly population.
引用
收藏
页数:8
相关论文
共 50 条
  • [1] Frailty Index and Frailty Phenotype in elderly patients with cancer
    van Deudekom, Floor J.
    van de Ruitenbeek, Marijke
    te Water, Wilma
    Smit, Jitty M.
    van Munster, Barbara C.
    [J]. ACTA ONCOLOGICA, 2016, 55 (05) : 644 - 646
  • [2] Correlates of frailty phenotype and frailty index and their associations with clinical outcomes
    Guaraldi, G.
    Malagoli, A.
    Theou, O.
    Brothers, T. D.
    Wallace, L. M. K.
    Torelli, R.
    Mussini, C.
    Sartini, S.
    Kirkland, S. A.
    Rockwood, K.
    [J]. HIV MEDICINE, 2017, 18 (10) : 764 - 771
  • [3] On comparisons of population and subpopulations in frailty models
    Da, Gaofeng
    Ding, Weiyong
    Li, Xiaohu
    [J]. COMMUNICATIONS IN STATISTICS-THEORY AND METHODS, 2020, 49 (15) : 3698 - 3711
  • [4] Frailty phenotype, frailty index and risk of mortality in Chinese elderly population- Rugao longevity and ageing study
    Shi, Guo-Ping
    Ma, Teng
    Zhu, Yin-Sheng
    Wang, Zheng-Dong
    Chu, Xue-Feng
    Wang, Yong
    Chen, Ze-Kun
    Xu, Wen-Dong
    Wang, Xiao-Feng
    Guo, Jiang-Hong
    Jiang, Xiao-Yan
    [J]. ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2019, 80 : 115 - 119
  • [5] The prevalence of frailty in elderly surgical patients and the effect of frailty on clinical outcomes
    Rahman, Sheila
    Bui, Triet
    Ngian, Vincent
    [J]. AUSTRALASIAN JOURNAL ON AGEING, 2021, 40 : 83 - 84
  • [6] Association between Frailty and Hypertension Prevalence, Treatment, and Control in the Elderly Korean Population
    Kang, Min-gu
    Kim, Sun-wook
    Yoon, Sol-Ji
    Choi, Jung-Yeon
    Kim, Kwang-il
    Kim, Cheol-Ho
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [7] Association between Frailty and Hypertension Prevalence, Treatment, and Control in the Elderly Korean Population
    Min-gu Kang
    Sun-wook Kim
    Sol-Ji Yoon
    Jung-Yeon Choi
    Kwang-il Kim
    Cheol-Ho Kim
    [J]. Scientific Reports, 7
  • [8] PREVALENCE OF FRAILTY IN A SPANISH ELDERLY POPULATION: THE FRAILTY AND DEPENDENCE IN ALBACETE STUDY
    Abizanda, Pedro
    Sanchez-Jurado, Pedro M.
    Romero, Luis
    Paterna, Gema
    Martinez-Sanchez, Esther
    Atienzar-Nunez, Pilar
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2011, 59 (07) : 1356 - 1359
  • [9] Multidimensional frailty in elderly emergency department patients: unveiling the prevalence and significance of social frailty
    Tsai, Yu-Chieh
    Huang, Edward Pei-Chuan
    Huang, Chien-Hua
    Chen, Ya-Mei
    [J]. CANADIAN JOURNAL OF EMERGENCY MEDICINE, 2024, 26 (08) : 549 - 553
  • [10] ASSOCIATION BETWEEN FRAILTY AND HYPERTENSION IN THE ELDERLY KOREAN POPULATION
    Kang, Min-gu
    Kim, Kwang-il
    [J]. JOURNAL OF HYPERTENSION, 2018, 36 : E169 - E169