Multiple granular cell tumor: A case report and review of the literature

Background. Granular cell tumor was first described by Abrikossoff in 1926. It is rare and usually presents as a benign solitary lesion. Multifocal and malignant forms are known to occur. Methods. This presentation illustrates an additional case of granular cell tumor. Clinical and histological features to distinguish malignant and benign forms are presented. Results. Tumor can develop years after therapy for the primary lesion. Treatment recommendations are presented. Conclusions. Patients diagnosed with granular cell tumor require close follow-up. Radiographic evaluation for the presence of metastatic disease is necessary if a malignant Variant is suspected. (C) 1997 John Wiley & Sons, Inc.