Rituximab treatment in primary angiitis of the central nervous system

被引:8
|
作者
Patel, Shreeya [1 ]
Ross, Laura [1 ,2 ]
Oon, Shereen [1 ,2 ]
Nikpour, Mandana [1 ,2 ]
机构
[1] St Vincents Hosp, Dept Rheumatol, Melbourne, Vic, Australia
[2] Univ Melbourne, St Vincents Hosp, Dept Med, Melbourne, Vic, Australia
关键词
primary angiitis of the central nervous system; vasculitis; rituximab; ANCA-ASSOCIATED VASCULITIS; EFFICACY; MAINTENANCE; COHORT; CNS;
D O I
10.1111/imj.13814
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary angiitis of the central nervous system (PACNS) is a rare autoimmune vasculitis affecting the brain and spinal cord. Treatment with biological agents has revolutionised the treatment of many rheumatic conditions but there is scant literature regarding the use of biological agents in PACNS. We present three cases of PACNS treated with rituximab, including two cases of relapsed disease, and a literature review suggesting a role for rituximab in this condition.
引用
收藏
页码:724 / 727
页数:4
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