Biosynthesis of vitamin B6 in Rhizobium

被引：15
|
作者：
Tazoe, M [1 ]
Ichikawa, K [1 ]
Hoshino, T [1 ]
机构：
[1] Nippon Roche Res Ctr, Dept Appl Microbiol, Kanagawa 2478530, Japan
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2000年 / 275卷 / 15期
关键词：
D O I：
10.1074/jbc.275.15.11300
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The biosynthetic pathway of pyridoxol (vitamin B-6) in Rhizobium was clarified by studies on the incorporation of C-13- or N-15-labeled precursors into pyridoxol or its biosynthetic intermediates. Pyridoxol was formed by ring closure of two compounds, 1-deoxy-D-xylulose and 4-hydroxy-L-threonine. The former was formed from D-glyceraldehyde and pyruvate through decarboxylation of pyruvate, and the latter from glycine and glycolaldehyde.
引用
收藏
页码：11300 / 11305
页数：6
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