Superficial siderosis of the central nervous system - treatment with steroids?

被引：8
|
作者：
Scheid, R. [1 ,2 ]
Frisch, S. [1 ]
Schroeter, M. L. [1 ,2 ]
机构：
[1] Univ Leipzig, Day Clin Cognit Neurol, D-04103 Leipzig, Germany
[2] Max Planck Inst Human Cognit & Brain Sci, Leipzig, Germany
来源：
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2009年 / 34卷 / 05期
关键词：
central nervous system; medication; steroids; superficial siderosis; treatment; THERAPY; ATAXIA;
D O I：
10.1111/j.1365-2710.2009.01030.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P>Steroids have been suggested as a therapeutic option for superficial siderosis of the central nervous system (SSCNS) without identifiable bleeding source. Longitudinal observational data of a patient with idiopathic SSCNS who was repeatedly treated with methylprednisolone over a course of 2 years are reported. The case history is critically discussed on the background of the sparse literature. In conclusion, if at all, there is only a limited and temporary, mostly subjective clinical response to steroids in SSCNS. Systematic studies of this medication in SSCNS do not seem warranted. Pathophysiological considerations hopefully may lead to more helpful medications for this chronic and debilitating disorder.
引用
收藏
页码：603 / 605
页数：3
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