Lactic Acid for Green Chemical Industry: Recent Advances in and Future Prospects for Production Technology, Recovery, and Applications

被引:31
|
作者
Kim, Jua [1 ]
Kim, Young-Min [2 ]
Lebaka, Veeranjaneya Reddy [3 ]
Wee, Young-Jung [1 ]
机构
[1] Yeungnam Univ, Dept Food Sci & Technol, Gyongsan 38541, South Korea
[2] Chonnam Natl Univ, Dept Food Sci & Technol, Gwangju 61186, South Korea
[3] Yogi Vemana Univ, Dept Microbiol, Kadapa 516003, Andhra Prades, India
来源
FERMENTATION-BASEL | 2022年 / 8卷 / 11期
关键词
biorefinery; lactic acid; fermentation; lignocellulose; engineered microorganisms; recovery; applications; REPEATED-BATCH FERMENTATION; OPTICALLY PURE D; SWEET SORGHUM JUICE; COIMMOBILIZED LACTOBACILLUS-CASEI; RECYCLE CONTINUOUS FERMENTATION; ENTEROCOCCUS-FAECALIS RKY1; PARACASEI SUBSP PARACASEI; D-LACTATE PRODUCTION; L(+)-LACTIC ACID; SIMULTANEOUS SACCHARIFICATION;
D O I
10.3390/fermentation8110609
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Lactic acid, an organic acid produced by numerous microorganisms, has many applications in the food, chemical, pharmaceutical, and polymer industries, with novel applications being developed particularly in the chemical industry. The lactic acid market has steadily grown with the introduction of novel and environmentally friendly products. Therefore, developing novel technologies for lactic acid production, with improved yield and reduced production costs, has become a major research goal. Utilization of inexpensive and renewable biomass is a major strategy for economically producing lactic acid. However, most lactic acid bacteria cannot directly utilize lignocellulosic biomass and require hydrolysis, which is costly. Immobilization techniques for large-scale production can enhance fermentation yield. Moreover, novel techniques, such as cell recycling systems and simultaneous saccharification, will enable microorganisms to produce lactic acid with increased concentration, yield, and productivity. Recently, genetic and metabolic engineering methods have been used for key solving problems, such as product inhibition, by-product formation, and suboptimal culture conditions, and for the effective use of cheap substrates. This review presents comprehensive insights into the most recent advances in the biological production of lactic acid from different substrates, bioprocess techniques for yield improvement, lactic acid purification, and applications of lactic acid for human welfare.
引用
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页数:34
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