The feasibility of RIMS for the analysis of potentially toxic element accumulation in neural tissue

被引:0
|
作者
Jones, OR
Abraham, CJ
Telle, HH
Oakley, AE
机构
来源
RESONANCE IONIZATION SPECTROSCOPY 1996 - EIGHTH INTERNATIONAL SYMPOSIUM | 1997年 / 388期
关键词
D O I
10.1063/1.52197
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
A feasibility study was conducted into the possibility of using resonance ionisation mass spectrometry for the detection of focal accumulation of neuro-toxic elements in neural tissue. Experiments were performed using a ToFMS system in conjunction with an Ar+ source for target sputtering and a pulsed tuneable dye laser system for resonance ionisation. Detection limits of similar to 3 ppm for Al in brain tissue homogenates were achieved, with a spatial resolution of less than 100 mu m.
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页码:289 / 292
页数:4
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