IGF-1 Deficiency Promotes Neurovascular Uncoupling: Implications for Cerebromicrovascular Aging and Age-Related Cognitive Decline

被引：0
|
作者：
Toth, Peter [1 ,2 ]
Tarantini, Stefano [1 ]
Ashpole, Nicole [1 ]
Valcarcel-Ares, Marta Noa [1 ]
Landoll, Jessica [1 ]
Tucsek, Zsuzsanna [1 ]
Milne, Ginger [3 ]
Sonntag, William [1 ]
Csiszar, Anna [1 ,2 ]
Ungvari, Zoltan [1 ,2 ]
机构：
[1] Univ Oklahoma HSC, Dept Geriatr Med, Reynolds Oklahoma Ctr Aging, Oklahoma City, OK USA
[2] Szentagothai Res Ctr, Dept Pathophysiol & Gerontol, Pecs, Hungary
[3] Vanderbilt Univ, Med Ctr, Nashville, TN USA
来源：
FASEB JOURNAL | 2015年 / 29卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
787.5
引用
收藏
页数：1
相关论文
共 50 条
  • [1] IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
    Toth, Peter
    Tarantini, Stefano
    Ashpole, Nicole M.
    Tucsek, Zsuzsanna
    Milne, Ginger L.
    Valcarcel-Ares, Noa M.
    Menyhart, Akos
    Farkas, Eszter
    Sonntag, William E.
    Csiszar, Anna
    Ungvari, Zoltan
    AGING CELL, 2015, 14 (06): : 1034 - 1044
  • [2] EXPERIMENTAL NEUROVASCULAR UNCOUPLING PROMOTES COGNITIVE IMPAIRMENT IN MICE: IMPLICATIONS FOR BRAIN AND CEREBROMICROVASCULAR AGING
    Tarantini, S.
    Tucsek, Z.
    Smith, N.
    Valcarcel-ares, M. N.
    Hodges, E.
    Towner, R.
    Deak, F.
    Sonntag, W. E.
    Csiszar, A.
    Toth, P.
    Ungvari, Z.
    JOURNAL OF VASCULAR RESEARCH, 2015, 52 : 52 - 52
  • [3] EXPERIMENTAL NEUROVASCULAR UNCOUPLING PROMOTES COGNITIVE IMPAIRMENT IN MICE: IMPLICATIONS FOR BRAIN AND CEREBROMICROVASCULAR AGING
    Tarantini, S.
    Zsuzsanna, T.
    Valcarcel-Ares, M.
    Nataliya, S.
    Farkas, E.
    Hodges, E.
    Towner, R.
    Deak, F.
    Sonntag, W.
    Csiszar, A.
    Toth, P.
    Ungvari, Z.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2016, 36 : 573 - 573
  • [4] Experimental Neurovascular Uncoupling Promotes Cognitive Impairment in Mice: Implications for Brain and Cerebromicrovascular Aging
    Tarantini, Stefano
    Tucsek, Zsuzsanna
    Smith, Nataliya
    Valcarcel-Ares, Marta Noa
    Hodges, Eric
    Towner, Rheal
    Deak, Ferenc
    Sonntag, William
    Csiszar, Anna
    Ungvari, Zoltan
    Toth, Peter
    FASEB JOURNAL, 2015, 29
  • [5] IGF-1 deficiency exacerbates hypertension-induced cerebromicrovascular rarefaction in mice: implications for cognitive decline
    Tarantini, Stefano
    Giles, Cory
    Toth, Peter
    Ashpole, Nicole M.
    Tucsek, Zsuzsanna
    Valcarcel-Ares, Marta Noa
    Gautam, Tripti
    Sonntag, William E.
    Wren, Jonathan D.
    Csiszar, Anna
    Ungvari, Zoltan
    FASEB JOURNAL, 2016, 30
  • [6] Aging Exacerbates Obesity-induced Cerebromicrovascular Rarefaction, Neurovascular Uncoupling, and Cognitive Decline in Mice
    Tucsek, Zsuzsanna
    Toth, Peter
    Tarantini, Stefano
    Sosnowska, Danuta
    Gautam, Tripti
    Warrington, Junie P.
    Giles, Cory B.
    Wren, Jonathan D.
    Koller, Akos
    Ballabh, Praveen
    Sonntag, William E.
    Ungvari, Zoltan
    Csiszar, Anna
    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2014, 69 (11): : 1339 - 1352
  • [7] Selective disruption of IGF-1 signaling in astrocytes impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
    Tarantini, Stefano
    Fulop, Gabor A.
    Yabluchanskiy, Andriy
    Kiss, Tamas
    Sonntag, William E.
    Csiszar, Anna
    Ungvari, Zoltan
    FASEB JOURNAL, 2018, 32 (01):
  • [8] Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults
    Luca Toth
    Andras Czigler
    Emoke Hegedus
    Hedvig Komaromy
    Krisztina Amrein
    Endre Czeiter
    Andriy Yabluchanskiy
    Akos Koller
    Gergely Orsi
    Gabor Perlaki
    Attila Schwarcz
    Andras Buki
    Zoltan Ungvari
    Peter J. Toth
    GeroScience, 2022, 44 : 2771 - 2783
  • [9] Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults
    Toth, Luca
    Czigler, Andras
    Hegedus, Emoke
    Komaromy, Hedvig
    Amrein, Krisztina
    Czeiter, Endre
    Yabluchanskiy, Andriy
    Koller, Akos
    Orsi, Gergely
    Perlaki, Gabor
    Schwarcz, Attila
    Buki, Andras
    Ungvari, Zoltan
    Toth, Peter J.
    GEROSCIENCE, 2022, 44 (06) : 2771 - 2783
  • [10] Age-related neurovascular coupling impairment is associated with cognitive decline in healthy individuals
    Lipecz, Agnes
    Csipo, Tamas
    Tarantini, Stefano
    Hand, Rachel A.
    Ngo, Bich-Thy N.
    Balasubramanian, Priya
    Kiss, Tamas
    Csiszar, Anna
    Ungvari, Zoltan
    Yabluchanskiy, Andriy
    FASEB JOURNAL, 2019, 33
12345