A comparison study of cognitive deficits in radiologically and clinically isolated syndromes

被引：41

作者：

Labiano-Fontcuberta, Andres ^{[1
]}

Luisa Martinez-Gines, Ma ^{[2
]}

Aladro, Yolanda ^{[3
]}

Ayuso, Lucia ^{[4
]}

Mitchell, Alex J. ^{[5
,6
]}

Puertas-Martin, Veronica ^{[1
]}

Cerezo, Marta ^{[3
]}

Higueras, Yolanda ^{[2
]}

Benito-Leon, Julian ^{[1
,7
,8
]}

机构：

[1] Univ Hosp 12 de Octubre, Dept Neurol, Madrid, Spain

[2] Univ Hosp Gregorio Maranon, Dept Neurol, Madrid, Spain

[3] Univ Hosp Getafe, Dept Neurol, Madrid, Spain

[4] Univ Hosp Principe de Asturias, Dept Neurol, Madrid, Spain

[5] Leicestershire Partnership Trust, Dept Psychol, Leicester, Leics, England

[6] Univ Leicester, Leicester LE1 7RH, Leics, England

[7] Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

[8] Univ Complutense, Dept Med, E-28040 Madrid, Spain

来源：

MULTIPLE SCLEROSIS JOURNAL | 2016年 / 22卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Clinically isolated syndrome; cognitive impairment; demyelinating disease; depression; information processing speed; radiologically isolated syndrome; FATIGUE IMPACT SCALE; USE D-FIS; MULTIPLE-SCLEROSIS; IMPAIRMENT; DISEASE;

D O I：

10.1177/1352458515591072

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Up until now, no information has existed regarding a comparison of the pattern and frequency of cognitive deficits between radiologically isolated syndrome (RIS) and clinically isolated syndrome (CIS) patients. Within this objective, Rao's Brief Repeatable Battery and Stroop test were administered to 28 RIS patients, 25 CIS patients, and 22 healthy controls. Conclusions: The prevalence of cognitive deficits in RIS was similar to that of CIS. Cognitive deficits seem to be present in RIS patients regardless of the presence of risk factors for a future symptomatic demyelinating event.

引用

页码：250 / 253

页数：4

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