Modes of regulation of RpoS by H-NS

被引:45
|
作者
Zhou, YanNing [1 ]
Gottesman, Susan [1 ]
机构
[1] NCI, Mol Biol Lab, Bethesda, MD 20892 USA
关键词
D O I
10.1128/JB.00687-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Regulated degradation of RpoS requires RssB and ClpXP protease. Mutations in hns increase both RpoS synthesis and stability, causing a twofold increase in synthesis and almost complete stabilization of RpoS, independent of effects on synthesis and independent of phosphorylation of RssB. This suggests that H-NS regulates an RssB inhibitor or inhibitors.
引用
收藏
页码:7022 / 7025
页数:4
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