Novel Synthesis of (E)-3-Arylidene-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-ones Using Baylis-Hillman Derivatives via Reductive Cyclization

被引：9
|
作者：
Bakthadoss, Manickam [1 ]
Murugan, Gandhi [1 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
来源：
SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 07期
关键词：
Baylis-Hillman reaction; benzoxazepinones; Fe; AcOH; 4-methyl; 2-nitrophenol; ADDUCTS; CONVENIENT; FRAMEWORKS;
D O I：
10.1080/00397910802519166
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple synthesis of novel (E)-3-arylidene-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-ones from bromides of the Baylis--Hillman adducts using Fe/AcOH for the in situ reduction of nitro group, into an amino group, followed by the cyclization as a key step, has been described.
引用
收藏
页码：1290 / 1298
页数：9
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