Emerging views about "osteoporosis", bone health, strength, fragility, and their determinants

被引:16
|
作者
Frost, HM [1 ]
机构
[1] So Colorado Clin, Dept Orthopaed Surg, Pueblo, CO 81008 USA
关键词
biomechanics; Utah paradigm; bone modeling; bone remodeling; fractures;
D O I
10.1007/s007740200046
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent articles by Drs. Lanyon, Raisz, Seeman, and Skerry summarized some emerging views about the causes and nature of some effects of mechanical loading on bones and "osteoporosis", the causes of fractures in that condition, and the causes of increased bone fragility and age-related bone loss. This article would supplement theirs with further evidence and ideas. This includes a definition of bone health that suggests currently popular classifications of "osteoporosis" and "osteopenia" could fail to distinguish healthy differences from normal averages from true bone diseases. This definition also suggests a classification of osteoporotic fractures that could question some current methods and uses of noninvasive absorptiometry. This article emphasizes concepts and generalities, and leaves resolution of any devils in the details to other places, times, and people.
引用
收藏
页码:319 / 325
页数:7
相关论文
共 50 条
  • [1] Emerging views about “osteoporosis”, bone health, strength, fragility, and their determinants
    Harold M. Frost
    [J]. Journal of Bone and Mineral Metabolism, 2002, 20 : 319 - 325
  • [2] Bone Quality: The Determinants of Bone Strength and Fragility
    Hélder Fonseca
    Daniel Moreira-Gonçalves
    Hans-Joachim Appell Coriolano
    José Alberto Duarte
    [J]. Sports Medicine, 2014, 44 : 37 - 53
  • [3] Bone Quality: The Determinants of Bone Strength and Fragility
    Fonseca, Helder
    Moreira-Goncalves, Daniel
    Coriolano, Hans-Joachim Appell
    Duarte, Jose Alberto
    [J]. SPORTS MEDICINE, 2014, 44 (01) : 37 - 53
  • [4] Determinants of bone fragility in preclinical studies of osteoporosis.
    Ammann, P
    Bonjour, JP
    Rizzoli, R
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 (04) : 826 - 826
  • [5] Emerging concepts in osteoporosis and bone strength
    Rubin, CD
    [J]. CURRENT MEDICAL RESEARCH AND OPINION, 2005, 21 (07) : 1049 - 1056
  • [6] Overview of osteoporosis: pathophysiology and determinants of bone strength
    Bono, CM
    Einhorn, TA
    [J]. EUROPEAN SPINE JOURNAL, 2003, 12 (Suppl 2) : S90 - S96
  • [7] Overview of osteoporosis: pathophysiology and determinants of bone strength
    Christopher M. Bono
    Thomas A. Einhorn
    [J]. European Spine Journal, 2003, 12 : S90 - S96
  • [8] Osteoporosis/bone fragility
    Napoli, Nicola
    Tramontana, Flavia
    [J]. JOURNAL OF GERONTOLOGY AND GERIATRICS, 2021, 69 (04): : 265 - 268
  • [9] HYALORETINAL DEGENERATION WITH OSTEOPOROSIS AND BONE FRAGILITY - PSEUDOGLIOMA WITH BONE FRAGILITY
    SAUVEGRAIN, J
    DUFIER, JL
    VACHER, H
    CHARLOT, JC
    PHUC, LHA
    HAYE, C
    [J]. JOURNAL DE RADIOLOGIE, 1981, 62 (10): : 537 - 543
  • [10] The bone quality framework: Determinants of bone strength and their interrelationships, and implications for osteoporosis management
    Felsenberg, D
    Boonen, S
    [J]. CLINICAL THERAPEUTICS, 2005, 27 (01) : 1 - 11