The electroolfactogram: A review of its history and uses

被引:108
|
作者
Scott, JW [1 ]
Scott-Johnson, PE
机构
[1] Emory Univ, Sch Med, Dept Cell Biol, Atlanta, GA 30322 USA
[2] Spelman Coll, Dept Psychol, Atlanta, GA 30314 USA
关键词
olfactory receptor neurons (ORNs); electroolfactogram (EOG); odor selection and delivery;
D O I
10.1002/jemt.10133
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
The electroolfactogram. (EOG) is a negative electrical potential recorded at the surface of the olfactory epithelium of vertebrates. It represents primarily, if not exclusively, the summated generator potential in the olfactory receptor neurons (ORNs). While a number of studies suggest that secretory or inhibitory events may also contribute to the EOG, these are not well established. This review outlines (1) the cellular and physiological nature of the EOG response; (2) methodological considerations regarding odor selection and delivery, surgical preparation, response descriptions, and analysis; and (3) application of the EOG in human, fish, and insect olfaction and pheromonal responsivity. A number of technical issues associated with EOG recording are also discussed.
引用
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页码:152 / 160
页数:9
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