Intestinal Tolerance, with a Little Help from Our Microbial Friends

被引:3
|
作者
Descamps, Helene [1 ,2 ]
Thaiss, Christoph A. [1 ,2 ]
机构
[1] Univ Penn, Microbiol Dept, Perelman Sch Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Inst Immunol, Perelman Sch Med, Philadelphia, PA 19104 USA
关键词
CELLS; IMMUNITY; COLITIS;
D O I
10.1016/j.immuni.2018.06.015
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The intestinal immune system performs a tightrope walk between anti-pathogen immunity and tolerance to innocuous luminal antigens. In this issue of Immunity, Kim et al. (2018) demonstrate that the microbiota is driving tolerance to food antigens and dampening inflammatory responses through CX(3)CR1(+) mononuclear phagocytes.
引用
收藏
页码:4 / 6
页数:3
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