High levels of tobacco-specific N-nitrosamines and nicotine in Chaini Khaini, a product marketed as snus

被引:25
|
作者
Stepanov, Irina [1 ,2 ]
Gupta, Prakash C. [3 ]
Dhumal, Gauri [3 ]
Yershova, Katrina [1 ]
Toscano, William [2 ]
Hatsukami, Dorothy [1 ]
Parascandola, Mark [4 ]
机构
[1] Univ Minnesota, Masonic Canc Ctr, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Div Environm Hlth Sci, Minneapolis, MN 55455 USA
[3] Healis Sekhsaria Inst Publ Hlth, Mumbai, Maharashtra, India
[4] Natl Canc Inst, Tobacco Control Res Branch, Bethesda, MD USA
关键词
Carcinogens; Nicotine; Harm Reduction; Packaging and Labelling; SMOKELESS TOBACCO; MOIST SNUFF; PUBLIC-HEALTH; CANCER; INDIA; EPIDEMIOLOGY; SMOKING; MOUTH; RISK; PH;
D O I
10.1136/tobaccocontrol-2014-051744
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Introduction Recently, a tobacco product, Chaini Khaini, identified as snus appeared in India. The product marketing emphasises its discreet nature and explicitly claims safety by referring to the existing evidence on Swedish snus. We analysed tobacco-specific nitrosamines and nicotine in 12 samples of Chaini Khaini purchased in 2013 at open markets in India. Methods Samples were purchased twice: in March 2013 from Mumbai and in November 2013 from Mumbai and Ahmedabad. Chemical constituents were measured by our routine validated methods. Results Levels of carcinogenic nitrosamines NNN, NNK and NNAL averaged 22.9 (4.9), 2.6 (+/- 1.0) and 3.1 (+/- 1.5)mu g/g tobacco (wet weight), respectively. The levels of NAB, which is normally present in trace levels in tobacco products, ranged from 3.9 to 12.9 mu g/g tobacco. Total nicotine levels in all samples averaged 10.0mg/g tobacco and unprotonated nicotine accounted for an average 95.4% of the total nicotine content. Conclusions Chaini Khaini, which is labelled as snus and is marketed as a safe alternative to other tobacco products contains very high levels of carcinogenic nitrosamines and biologically available nicotine. Interventions are urgently needed to educate current and potential consumers of this product.
引用
收藏
页码:E271 / E274
页数:4
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