KRAS Mutations Are Frequently Identified in Colorectal Carcinoma with BRAF Wild-Type Sporadic MLH1 deficiency from MLH1 Promoter Hypermethylation

被引：0
|
作者：
Farchoukh, Lama [1 ]
Pai, Reetesh K. [1 ]
Kuan, Shih-Fan [1 ]
机构：
[1] Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA
来源：
LABORATORY INVESTIGATION | 2016年 / 96卷
关键词：
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
673
引用
收藏
页码：170A / 171A
页数：2
相关论文
共 50 条
  • [1] KRAS Mutations Are Frequently Identified in Colorectal Carcinoma with BRAF Wild-Type Sporadic MLH1 deficiency from MLH1 Promoter Hypermethylation
    Farchoukh, Lama
    Pai, Reetesh K.
    Kuan, Shih-Fan
    MODERN PATHOLOGY, 2016, 29 : 170A - 171A
  • [2] MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas
    Farchoukh, Lama
    Kuan, Shih-Fan
    Dudley, Beth
    Brand, Randall
    Nikiforova, Marina
    Pai, Reetesh K.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2016, 40 (10) : 1390 - 1399
  • [3] Histopathological Features of MLH1-deficient Colorectal Carcinoma with Wild-type BRAF and MLH1 Promoter Hypermethylation
    Stakelum, A.
    Ryan, E.
    Geraghty, R.
    Sheahan, K.
    Winter, D.
    BRITISH JOURNAL OF SURGERY, 2020, 107 : 16 - 16
  • [4] Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions
    Cocco, Emiliano
    Benhamida, Jamal
    Middha, Sumit
    Zehir, Ahmet
    Mullaney, Kerry
    Shia, Jinru
    Yaeger, Rona
    Zhang, Liying
    Wong, Donna
    Villafania, Liliana
    Nafa, Khedoudja
    Scaltriti, Maurizio
    Drilon, Alexander
    Saltz, Leonard
    Schram, Alison M.
    Stadler, Zsofia K.
    Hyman, David M.
    Benayed, Ryma
    Ladanyi, Marc
    Hechtman, Jaclyn F.
    CANCER RESEARCH, 2019, 79 (06) : 1047 - 1053
  • [5] MLH1 promoter hypermethylation in endometrial carcinoma.
    Honore, LH
    Otto, C
    Helmle, K
    Whiteside, D
    Andrew, SE
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 258 - 258
  • [6] Microsatellite instability and MLH1 promoter hypermethylation in colorectal cancer
    Niv, Yaron
    WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (12) : 1767 - 1769
  • [7] Microsatellite instability and MLH1 promoter hypermethylation in colorectal cancer
    Yaron Niv
    World Journal of Gastroenterology, 2007, (12) : 1767 - 1769
  • [8] IS REFLEX MLH1 PROMOTER HYPERMETHYLATION TESTING FOLLOWING MLH1 LOSS BY IMMUNOHISTOCHEMISTRY IN ENDOMETRIAL CARCINOMA BEST PRACTICE?
    Plotkin, Anna
    Olkhov-Mitsel, Ekaterina
    Nofech-Mozes, Sharon
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2022, 32 : A26 - A27
  • [9] Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers
    Miyakura Y.
    Tahara M.
    Lefor A.T.
    Yasuda Y.
    Sugano K.
    BMC Research Notes, 7 (1)
  • [10] MLH1 promoter hypermethylation and Lynch Syndrome: When to test for constitutional epimutations of MLH1 gene?
    Cazzaniga, Laura
    Zanzottera, Cristina
    Mannucci, Sara
    Fava, Francesca
    Marabelli, Monica
    Calvello, Mariarosaria
    Feroce, Irene
    Risti, Matilde
    Manna, Eliza Del Fiol
    Bertario, Lucio
    Serrano, Davide
    Bonanni, Bernardo
    TUMORI JOURNAL, 2025,
12345