A new scaffold for dipeptide β-turn mimetics:: Expeditious synthesis of an unsaturated 6,5-fused bicyclic lactam

被引：6
|
作者：
Millet, R
Houssin, R
Hénichart, JP
Rigo, B
机构：
[1] Univ Lille 2, Inst Chim Pharmaceut, F-59006 Lille, France
[2] Ecole Hautes Etud Ind, Organ Synth Lab, F-59046 Lille, France
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1999年 / 36卷 / 05期
关键词：
D O I：
10.1002/jhet.5570360527
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reported here is an easy and short synthesis of 6-acetamido-5-axo-1,2,3,5,6,7-hexahydro-3-indolizine-carboxylic acid, originating from beta-enaminoesters derived from pyroglutamic acid. This key compound has been used as a scaffold in the synthesis of dipeptido mimetics.
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收藏
页码：1279 / 1284
页数：6
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