Review of modern diagnostic methods for glaucoma suspects and glaucoma patients

Background: Diagnosis of early glaucomatous damage as well as the detection of glaucomatous change are still difficult tasks. During the last years numerous new diagnostic techniques have been investigated and some of them have been introduced to the market. Methods: This paper reviews the different aims of diagnostic technologies in the field of glaucoma. Methods appearing suitable for a large-scale use by ophthalmologists will be judged according to their suitability to meet the goals of early diagnosis, objective diagnosis, progression analysis and screening. Conclusions: The new diagnostic techniques have not yet greatly influenced our diagnostic procedure. This is mainly due to the fact that, for the most difficult borderline cases of glaucoma, these methods are of limited value, or have not yet been sufficiently investigated. Nevertheless, the Heidelberg retina tomograph (HRT), the nerve fiber analyzer GDX, short wavelength perimetry (SWAP), and the frequency doubling test (FDT) may play a role in these cases. For follow-up, HRT and GDx have proven valuable, especially in early stages of the disease. The very short testing time of FDT together with good specificity qualifies this test for glaucoma screening.