Two new triterpenoids from Azadirachta indica and their insecticidal activity

被引：27
|
作者：
Siddiqui, BS [1 ]
Afshan, F
Faizi, S
Naqvi, SNH
Tariq, RM
机构：
[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan
[2] Baqai Med Univ, Dept Pharmacol, Karachi, Pakistan
[3] Univ Karachi, Dept Zool, Karachi 75270, Pakistan
来源：
JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 08期
关键词：
D O I：
10.1021/np0105477
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new triterpenoids, 22,23-dihydronimocinol (1) and desfurano 6alpha hydroxyazadiradione (2), were isolated from a methanolic extract of the fresh leaves of Azadirachta indica (neem) along with a known meliacin, 7alpha senecioyl-(7-deacetyl)-23 O methylnimocinolide The structures of 1 and 2 were elucidated through spectral and chemical studies Compounds 1 and 2 showed mortality for fourth instar larvae of the mosquito (Anopheles stephensi), with LC50 values of 60 and 43 ppm, respectively.
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收藏
页码：1216 / 1218
页数：3
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