Triazolopyridines 23.: Synthesis of 5,5′-bi[1,2,3]triazolo[5,1-a]isoquinoline

被引：6

作者：

Abarca, B ^{[1
]}

Ballesteros, R ^{[1
]}

Gay, B ^{[1
]}

Domínguez, JR ^{[1
]}

机构：

[1] Univ Valencia, Fac Farm, Dept Quim Organ, Avda Vicente Andres Estelles S-N, Valencia 46100, Spain

来源：

ARKIVOC | 2004年

关键词：

bitriazoloisoquinolines; triazoloisoquinolines; lithiation reaction; self-coupling and cross-coupling reactions;

D O I：

10.3998/ark.5550190.0005.406

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5,5'-Bi[1,2,3] triazolo[5,1-a] isoquinoline 6 has been synthesised from [1,2,3] triazolo[5,1-a] isoquinoline 5 by four procedures, dimerisation by LDA, Stille and Suzuki self-coupling reactions, and Suzuki cross-coupling reaction. The last is the best. Compound 6 gives 1,1'-bi(acetoxymethyl)-3,3'-biisoquinoline 10 by triazolo ring opening by acetic acid.

引用

页码：42 / 47

页数：6

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