Function and interaction of maturation-promoting factor and mitogen-activated protein kinase during meiotic maturation and fertilization of oocyte

被引：0
|
作者：
Huo, LJ [1 ]
Fan, HY [1 ]
Chen, DY [1 ]
Sun, QY [1 ]
机构：
[1] Chinese Acad Sci, Inst Zool, State Key Lab Reprod Biol, Beijing 100080, Peoples R China
来源：
PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL | 2004年 / 14卷 / 07期
关键词：
oocyte; meiosis; fertilization; MAP kinase; MPF;
D O I：
10.1080/10020070412331343951
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Mitogen-activated protein kinase (MAP kinase) cascade and maturation-promoting factor (MPF) play very important roles during meiotic maturation and fertilization of oocyte. Interaction between MAP kinase and MPF influences meiotic maturation and fertilization of oocyte throughout the animal kingdom, including stimulation of germinal vesicle breakdown (GVBD), suppression of DNA replication, control of meiotic chromosome segregation, maintenance of metaphase 11 arrest, and resumption and completion of second meiosis. This review focuses on the function and interaction of MAP kinase and MPF during meiotic maturation and fertilization of oocyte.
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页码：562 / 567
页数：6
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