Effects of gastric bypass on estimated cardiovascular risk in morbidly obese patients with metabolic syndrome

Introduction: The major goal of surgical treatment in morbid obesity is to decrease morbidity and mortality associated with excess weight. In this sense, the main factors of death are cardiovascular disease and metabolic syndrome. The objective of this study is to evaluate the effects of gastric bypass on cardiovascular risk estimation in patients after bariatric surgery. Material and methods: We retrospectively evaluated pre and postoperative cardiovascular risk estimation of 402 morbidly obese patients who underwent laparoscopic gastric bypass. The major variable studied is the cardiovascular risk estimation that is calculated preoperatively and after 12 months. Cardiovascular risk estimation analysis has been performed with the REGICOR Equation. REGICOR formulation allows calculating a 10 year risk of cardiovascular events adapted to the Spanish population and is expressed in percentages. Results: We reported an overall 4.1 +/- 3.0 mean basal REGICOR score. One year after the operation, cardiovascular risk estimation significantly decreased to 2,2 +/- 1,6 (P < .001). In patients with metabolic syndrome according to ATP-III criteria, basal REGICOR score was 4.8 +/- 3.1 whereas in no metabolic syndrome patients 2.2 +/- 1.8. Evaluation 12 months after surgery, determined a significant reduction in both groups (metabolic syndrome and non metabolic syndrome) with a mean REGICOR score of 2.3 +/- 1.6 and 1.6 +/- 1.0 respectively. Conclusion: The results of our study demonstrate favorable effects of gastric bypass on the cardiovascular risk factors included in the REGICOR equation. (C) 2013 AEC. Published by Elsevier Espana, S. L. All rights reserved.