Preliminary Evaluation of the Research-Use-Only (RUO) iCubate iC-GPC Assay for Identification of Select Gram-Positive Bacteria and Their Resistance Determinants in Blood Culture Broths

被引：7
|
作者：
Buchan, Blake W. [1 ,2 ]
Reymann, Garrett C. [2 ]
Granato, Paul A. [3 ,4 ]
Alkins, Brenda R. [3 ]
Jim, Patricia [5 ]
Young, Stephen [5 ,6 ]
机构：
[1] Med Coll Wisconsin, Dept Pathol, Milwaukee, WI 53226 USA
[2] Wisconsin Diagnost Lab, Milwaukee, WI USA
[3] Lab Alliance Cent New York, Liverpool, NY USA
[4] SUNY Upstate Med Univ, Dept Pathol, Syracuse, NY 13210 USA
[5] Tricore Reference Lab, Albuquerque, NM USA
[6] Univ New Mexico, Dept Pathol, Albuquerque, NM 87131 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2015年 / 53卷 / 12期
关键词：
IN-SITU HYBRIDIZATION; LASER-DESORPTION/IONIZATION-TIME; GENEOHM STAPHSR ASSAY; STAPHYLOCOCCUS-AUREUS; S; AUREUS; POTENTIAL IMPACT; RAPID DETECTION; MARKERS; THERAPY; BOTTLES;
D O I：
10.1128/JCM.01934-15
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The iC-GPC assay (iCubate, Huntsville, AL) provides a molecular option for the rapid, on-demand analysis of positive blood cultures. A preliminary evaluation of the iC-GPC assay using 203 clinical or seeded specimens demonstrated a sensitivity of 93.8% to 100% and a specificity of 98.0% to 100% for the identification of five Gram-positive bacterial species (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Enterococcus faecalis, and Enterococcus faecium) and three associated genetic resistance determinants (mecA, vanA, and vanB) in positive blood culture broths.
引用
收藏
页码：3931 / 3934
页数：4
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